© March of Dimes Some 1.7 million US children participate in field trials of Salk's IPV. The next year, children celebrate the vaccine's success as IPV is approved for general use. It would play the decisive role in blocking wild polio transmissions in North America. In 1954, three US scientists win the Nobel Prize in Physiology for their discovery that polio can grow in various tissue types. This paved the way for mass manufacturing of the vaccine.